Windows Server 2016 compatibility with McAfee products

McAfee is committed to supporting the Microsoft release cadence for Windows Server 2016


Multiple McAfee business and enterprise products
Microsoft Windows Server 2016


McAfee is committed to supporting the Microsoft release cadence for Windows Server 2016, and we are working closely with Microsoft to ensure that McAfee software and hardware products are fully compatible with Windows Server 2016.

To ensure release quality, all new releases that Microsoft publishes for Windows Server 2016 require full validation by the individual product teams. Our goal is to provide zero-day support for all Windows Server 2016 releases over time for those products that do not currently offer this cadence.

Any late-breaking changes that Microsoft implements to a release, or any unresolved compatibility issues raised by McAfee with Microsoft around a scheduled release, might lead to schedule changes. Schedule changes will be documented and updated in this article. Additional information about Windows Server 2016 support for McAfee products will use standard communication methods including the Support Notification Service (SNS).

Date Update
January 16, 2017 Updates to Security for Lotus Domino. New footnote 4 added to cover Server Core.
December 15, 2017 Added McAfee Security for Microsoft SharePoint 3.5 and VirusScan Enterprise for Storage 1.3.0.
October 27, 2017 Updated DLP Endpoint to Pending Update.
October 19, 2017 Added VirusScan for Storage. Currently under review with the product development team.
April 6, 2017 McAfee rebrand changes. No new content.

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  • Future release dates are subject to change.
  • NOTE: Any future product functionality or releases mentioned in the Knowledge Base are intended to outline our general product direction and should not be relied on, either as a commitment, or when making a purchasing decision.
  • RTW = Released To World
  • RTS = Released To Support, also called Managed Release. Contact Technical Account Manager (TAM) or Support Account Manager (SAM) if you want to participate in a Managed Release program.
  • For details about Service Packs, patches, hotfixes, maintenance releases, and the patch release cycle, see KB51560.

McAfee Products Windows 2016 Standard
Minimum Supported Version
Windows 2016 Data Center
Minimum Supported Version
Endpoint Protection Products
Active Response Pending Update Pending Update
Application and Change Control 8.0.1
Q1 2018
Q1 2018
Data Loss Prevention Endpoint (DLP Endpoint) Pending Update Pending Update
Endpoint Security (ENS) 10.2 (RTW)
10.1.2 (RTW)
10.2 (RTW)
10.1.2 (RTW)
Host Intrusion Prevention (Host IPS) 8.0 Patch 8 (RTW) 8.0 Patch 8 (RTW)
SiteAdvisor Enterprise (SAE) 3.5 Patch 5 (RTW) 3.5 Patch 5 (RTW)
Threat Intelligence for Endpoint Security Client Pending Update Pending Update
Threat Intelligence Exchange (TIE) Module for VSE 1.0.2 (RTW) 1.0.2 (RTW)
VirusScan Command Line Scanner Pending Update Pending Update
VirusScan Enterprise (VSE) 8.8 Patch 8 Hotfix 1159675 3 8.8 Patch 8 Hotfix 1159675 3
VirusScan Enterprise for Storage 1.3.0 (RTW January 2018) 1.3.0 (RTW January 2018)
Database Security Products
Database Activity Monitoring (Standalone Management) Pending Update Pending Update
Database Activity Monitoring (ePO Management) Pending Update Pending Update
Vulnerability Manager for Databases (Standalone Management) Pending Update Pending Update
Vulnerability Manager for Databases (ePO Management) Pending Update Pending Update
Data Center Protection Products
Management for Optimized Virtual Environment (MOVE) Multi-Platform 4.5 (Dec 2016) 4.5 (RTW)
Data Protection Products
Drive Encryption (DE) 7.2.0 (RTW)
DE 7.1.3 HF1148978
7.2.0 (RTW)
DE 7.1.3 HF1148978
File and Removable Media Protection (FRP) 5.0.2 2 5.0.2 2
Management of Native Encryption (MNE) 4.0.0 (RTW) 4.0.0 (RTW)
Security Management Products
Data Exchange Layer (DXL) 2.0.0 (RTW) 2.0.1 Patch 1 (RTW)
McAfee Agent (MA) 5.0.4
4.8.0 Patch 3
4.8.0 Patch 3
Policy Auditor Agent (PA) 1 1
Rogue System Detection 5.0.4 5.0.4
Web Protection    
McAfee Client Proxy (MCP) 2.1 (RTW) 2.1 (RTW)
Mail Gateway Protection    
McAfee Security for Microsoft SharePoint4 3.5 3.5
McAfee Security for Microsoft Exchange (MSME)4 8.5.1 8.5.1
McAfee Security for Lotus Domino4 7.5.3 7.5.3
1 For the Policy Auditor Agent, the November 2016 content update is required.
2 IMPORTANT: FRP is not supported on Windows Servers; the reference in this table is used only for network share testing.
3 VSE 8.8 Patch 8 Hotfix 1159675 is not supported when Windows Server 2016 is installed in either Server Core or Nano Server mode. For details of a known issue, see KB88819.
4 Windows 2016 versions are supported except Windows 2016 Server Core.